Sulfurization Reagents for Oligonucleotide Synthesis (5)

Xanthane Hydride Beaucage Reagent Phenyl acetyl disulfide (PADS) Camphorsulfonyl oxaziridine (CSO) N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide (DDTT)

UnyLinker Attached to Succinyl-lcaa-Polystyrene (Low Level to High Level Loading; 10-350µm/g) (2) GalNAc Polystyrene Support (1) LNA attached to Solid Support - High Loaded Polystyrene (6)

DMT-N-Phenyl-UnylinkerSuccinyl-lcaa-Polystyrene DMT-Methyl-UnylinkerSuccinyl-lcaa-Polystyrene

GalNAc-L96-UnyLinker Succinyl lcaa-Polystyrene support

LNA-Adenosine (N-bz)- High Loaded Polystyrene Support LNA-Cytidine (N-Ac)- High Loaded Polystyrene Support LNA-5-Methyl Cytidine (N-bz)- High Loaded Polystyrene Support LNA-Guanosine (N-ibu)- High Loaded Polystyrene Support LNA-Guanosine (N-dmf)- High Loaded Polystyrene Support LNA-Thymidine- High Loaded Polystyrene Support

1,2 dideoxy D-ribose 3-DMT-5-lcaa CPG 500A⁰ ( Reverse Abasic CPG 500A⁰ ) (1) GalNAc CPG (2) Biotin (tb) 3’-lcaa CPG 500A⁰ (1) 3’-DMT Thymidine 5’-lcaa CPG (1) Thiol-Modifier C6 S-S CPG (1) 3’-Amino-Modifier CPG (4) Unylinker CPG Support for Oligonucleotide (4) CPG Support for Silyl RNA (8) CPG Support for 2'-TOM RNA (4) CPG Support for 2'-OMethyl RNA (7) CPG Support for 2'-Fluoro DNA (5) CPG Support for Natural DNA (7) 3’-Phosphate-ON-lcaa-CPG (1) Native Amino lcaa CPG (1) 6-FAM CPG Support (1) 6-TAMRA -Support (1) 5-TAMRA -Support (1) Tetrachloro-fluorescein (TET) Support (1) Hexachloro-fluorescein (HEX) Support (1) Cyanine 550 Support (1) Cyanine 650 Support (1) Cyanine 3.5 Support (1)

1,2 dideoxy D-ribose 3-DMT-5-lcaa CPG 500A⁰

GalNAc-L96-UnyLinker Succinyl-lcaa-CPG support GalNAc-C3-UnyLinker Succinyl lcaa-CPG support

Biotin (tb) 3’-lcaa CPG 500A⁰

3’-DMT Thymidine 5’-lcaa CPG 1000A⁰

Thiol-Modifier C6 S-S CPG

TFA-3'-Amino - Modifier CPG Fmoc-3'-Amino-Modifier CPG 3'-Amino Modifier C-3 lcaa CPG 3'-PT-Amino Modifier C6 CPG

N-Methyl-Universal Unylinker-Succinyl-lcaa-CPG Support (DMT-ON) N-Methyl-Universal Unylinker-Succinyl-lcaa-CPG Support (DMT-OFF) N-Phenyl-Universal Unylinker-Succinyl-lcaa-CPG Support (DMT-ON) N-Phenyl-Universal Unylinker-Succinyl-lcaa-CPG Support(DMT-OFF)

2’-O-tBDSilyl-Adenosine(N-Ac)-3’-lcaa-CPG 2’-O-tBDSilyl-Adenosine(N-bz)-3’-lcaa-CPG 2’-O-tBDSilyl-Cytidine(N-bz)-3’-lcaa-CPG 2’-O-tBDSilyl-Cytidine(N-Ac)-3’-lcaa-CPG 2’-O-tBDSilyl-Guanosine(N-Ac)-3’-lcaa-CPG 2’-O-tBDSilyl-Guanosine(N-ibu)-3’-lcaa-CPG 2’-O-tBDSilyl-Guanosine(N-dmf)-3’-lcaa-CPG 2’-O-tBDSilyl-Uridine-3’-lcaa-CPG

2’-TOM Adenosine(N-Ac)-3’-lcaa-CPG 2’-TOM Cytidine(N-Ac)-3’-lcaa-CPG 2’-TOM Guanosine(N-Ac)-3’-lcaa-CPG 2’-TOM Uridine -3’-lcaa-CPG

2’-O-Methyl-Adenosine(N-bz)-3’-lcaa-CPG 2’-O-Methyl-Cytidine(N-bz)-3’-lcaa-CPG 2’-O-Methyl-Cytidine(N-Ac)-3’-lcaa-CPG 2’-O-Methyl-Guanosine(N-ibu)-3’-lcaa-CPG 2’-O-Methyl-Guanosine(N-dmf)-3’-lcaa-CPG 2’-O-Methyl-Guanosine(N-Ac)-3’-lcaa-CPG 2’-O-Methyl-Uridine-3’-lcaa-CPG

2’-Fluoro-deoxyAdenosine (N-bz)-3’-lcaa-CPG 2’-Fluoro-deoxyCytidine (N-bz)-3’-lcaa-CPG 2’-Fluoro-deoxyCytidine (N-Ac)-3’-lcaa-CPG 2’-Fluoro-deoxyGuanosine(N-ibu)-3’-lcaa-CPG 2’-Fluoro-deoxyUridine-3’-lcaa-CPG

2’-deoxyAdenosine (N-bz)-3’-lcaa-CPG 2’-deoxyCytidine(N-bz)-3’-lcaa-CPG 2’-deoxyCytidine (N-Ac)- 3’-lcaa-CPG 2’-deoxyGuanosine (N-Ac)-3’-lcaa-CPG 2’-deoxyGuanosine (N-ibu)-3’-lcaa-CPG 2’-deoxyGuanosine (N-dmf)-3’-lcaa-CPG Thymidine-3’-lcaa-CPG

3’-Phosphate-ON-lcaa-CPG

Native Amino lcaa CPG

6-FAM CPG Support

6-TAMRA -Support

5-TAMRA -Support

Tetrachloro-fluorescein (TET) Support

Hexachloro-fluorescein (HEX) Support

Cyanine 550 Support

Cyanine 650 Support

Cyanine 3.5 Support

RNA Dimer Phosphoramidites (16)

5'-O-DMT-2'-TOM-rC(N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rC(N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rA(N-Ac)-3'-5'- CNEt phosphate -2'-TOM-rA(N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rG (N-Ac)-3' -5'-CNEt phosphate-2'-TOM-rG (N-Ac) -3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rU-3'-5'-CNEt phosphate -2'-TOM-rU-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rU-3'-5'-CNEt phosphate-2'-TOM-rC (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rU-3'-5'-CNEt phosphate-2'-TOM-rA (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rU-3'-5'-CNEt phosphate-2'-TOM-rG (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rC (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rU-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rC (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rA (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rC (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rG (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rA (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rU-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rA (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rC (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rA (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rG (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rG (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rU-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rG (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rC (N-Ac)-3'-CNEt phosphoramidite 5'-O-DMT-2'-TOM-rG (N-Ac)-3'-5'-CNEt phosphate-2'-TOM-rA (N-Ac)-3'-CNEt phosphoramidite

2’-OCF3 Phosphoramidites (3)

2’-OCF3 CYTIDINE PHOSPHORAMIDITE 2’-OCF3-GUANOSINE-PHOSPHORAMIDITE 2’-OCF3-URIDINE-PHOSPHORAMIDITE

DMPx-Phosphoramidites (4) 2’-F-Ana-Cytidine(N-Ac)-phosphoramidite (1) Thiol-Modifier C6 S-S phosphoramidite (1) 5'-Amino modifier C6 (2) CET-Phosphoramidites (5) Fmoc-Amino-DMT C-3 CED phosphoramidite (1) GNA-phosphoramidite (5) POM-Phosphoramidite (4) Fmoc-Amino-DMT C-7 CE phosphoramidite (1) Reverse Abasic Phosphoramidite (1) 2’-TOM RNA Phosphoramidites (4) 2’-TOM β-L- RNA Phosphoramidites (4) 2’-O-tBDSilyl RNA Phosphoramidites (9) 2’-O-tBDSilyl Labile Base RNA Phosphoramidites (3) 3’-O-tBDsilyl RNA Phosphoramidites (7) 2’-O-Methyl RNA Phosphoramidites (9) 3’-O-Methyl RNA Phosphoramidites (6) 2’-O-MOE RNA Phosphoramidites (7) 2’-Fluoro -2'-deoxy Phosphoramidites (7) 7-deaza -2'-deoxy Phosphoramidites (3) 7-deaza-2'-O-tBDSilyl RNA Phosphoramidites (3) 7-deaza-2’-O-Methyl RNA Phosphoramidites (3) LNA(Locked Nucleic Acids)- Phosphoramidites (8) Natural DNA Phosphoramidites (9) Natural Mild Base Protected DNA Phosphoramidites (3) GalNAc Phosphoramidites (2) Pseudouridine , N1-Me- Pseudouridine Phosphoramidites (2) 5-Methyl-deoxy Phosphoramidites (2)

5’-O-DMPx-2’-dA(N-bz)-3’-CEP 5’-O-DMPx-2’-dC(N-Ac)-3’-CEP 5’-O-DMPx-2’-dG(N-dmf)-3’-CEP 5’-O-DMPx-2’-dT-3’-CEP

2’-F-Ana-Cytidine(N-Ac)-phosphoramidite

Thiol-Modifier C6 S-S phosphoramidite

5'-Amino modifier C6 Phosphoramidite 5'-TFA-Amino Modifier C6- 3'-CEP

CET-Adenosine (N-bz)-3’-CEP CET-Guanosine (N-ibu)-3’-CEP CET-5-Me-Uridine -3’-CEP CET-Uridine -3’-CEP CET-5-Me-Cytidine (N-bz)-3’-CEP

Fmoc-Amino-DMT C-3 CED phosphoramidite

GNA-S-A(bz)-phosphoramidite GNA-S-C(Ac)-phosphoramidite GNA-S-G(ibu)-phosphoramidite GNA-S-U-phosphoramidite GNA-S-T-phosphoramidite

5'-POM-(E)-VP-2'-OMe-A(bz)-Phosphoramidite 5'-POM-(E)-VP-2'-OMe-C(bz)-Phosphoramidite 5'-POM-(E)-VP-2'-OMe-G(ibu)-Phosphoramidite 5'-POM-(E)-VP-2'-OMe-U-Phosphoramidite

Fmoc-Amino-DMT C-7 CE phosphoramidite

Reverse Abasic Phosphoramidite

2’-TOM-Adenosine (N-Ac)-3’-CEP 2’-TOM-Cytidine (N-Ac)-3’-CEP 2’-TOM-Guanosine (N-Ac)-3’-CEP 2’-TOM-Uridine-3’-CEP

2’-TOM-β-L-Adenosine (N-Ac)-3’-CEP 2’-TOM-β-L-Cytidine (N-Ac)-3’-CEP 2’-TOM-β-L-Guanosine (N-Ac)-3’-CEP 2’-TOM-β-L-Uridine-3’-CEP

2’-O-tBDsilyl-Adenosine (N-bz)-3’-CEP 2’-O-tBDsilyl-Adenosine (N-Ac)-3’-CEP 2’-O-tBDsilyl-Cytidine (N-Ac)-3’-CEP 2’-O-tBDsilyl-Cytidine (N-bz)-3’-CEP 2’-O-tBDsilyl-Guanosine (N-Ac)-3’-CEP 2’-O-tBDsilyl-Guanosine (N-ibu)-3’-CEP 2’-O-tBDsilyl-Guanosine (N-dmf)-3’-CEP 2’-O-tBDsilyl-Uridine-3’-CEP 6-OXO-Uridine-3’-CEP

2’-O-tBDsilyl-Adenosine (N-PAc)-3’-CEP 2’-O-tBDsilyl-Cytidine (N-PAc)-3’-CEP 2’-O-tBDsilyl-Guanosine (N-PAc)-3’-CEP

3’-O-tBDsilyl-Adenosine (N-bz) Phosphoramidite 3’-O-tBDsilyl-Adenosine (N-Ac) Phosphoramidite 3’-O-tBDsilyl-Cytidine (N-bz) Phosphoramidite 3’-O-tBDsilyl-Cytidine (N-Ac) Phosphoramidite 3’-O-tBDsilyl-Guanosine (N-Ac) Phosphoramidite 3’-O-tBDsilyl-Guanosine (N-ibu) Phosphoramidite 3’-O-tBDsilyl-Uridine Phosphoramidite

2’-O-Methyl -Adenosine (N-bz)-3’-CEP 2’-O-Methyl-Cytidine (N-bz)-3’-CEP 2’-O-Methyl-Cytidine (N-Ac)-3’-CEP 2’-O-Methyl-C-5-Methyl-Cytidine (N-bz)-3’-CEP 2’-O-Methyl-Guanosine (N-ibu)-3’-CEP 2’-O-Methyl-Guanosine (N-dmf)-3’-CEP 2’-O-Methyl-Guanosine (N-Ac)-3’-CEP 2’-O-Methyl-Uridine-3’-CEP 2’-O-Methyl-C-5-Methyl-Uridine-3’-CEP

3’-O-Methyl -Adenosine (N-bz) Phosphoramidite 3’-O-Methyl -Cytidine (N-Ac) Phosphoramidite 3’-O-Methyl -Cytidine (N-bz) Phosphoramidite 3’-O-Methyl -Guanosine (N-Ac) Phosphoramidite 3’-O-Methyl -Guanosine (N-ibu) Phosphoramidite 3’-O-Methyl-Uridine Phosphoramidite

2’-MOE-Adenosine (N-bz)-3’-CEP 2’-MOE-Cytidine (N-bz)-3’-CEP 2’-MOE-C-5-Methyl-Cytidine (N-bz)-3’-CEP 2’-MOE-Guanosine (N-ibu)-3’-CEP 2’-MOE-Guanosine (N-dmf)-3’-CEP 2’-MOE-Uridine-3’-CEP 2’-MOE-C-5-Methyl-Uridine-3’-CEP

2’-Fluoro-Deoxy-Adenosine (N-bz)-3’-CEP 2’-Fluoro-Deoxy-Cytidine (N-Ac)-3’-CEP 2’-Fluoro-Deoxy-Cytidine (N-bz)-3’-CEP 2’-Fluoro-C-5-Methyl-Deoxy-Cytidine (N-bz)-3’-CEP 2’-Fluoro-Deoxy-Guanosine (N-ibu)-3’-CEP 2’-Fluoro-Thymidine-3’-CEP 2’-Fluoro-Deoxy-Uridine-3’-CEP

7-deaza-2’-Deoxy-Adenosine (N-bz)-3’-CEP 7-deaza-2’-Deoxy-Guanosine (N-ibu)-3’-CEP 7-deaza-2’-Deoxy-Guanosine (N-Ac)-3’-CEP

2’-O-tBDSilyl-7-deaza-Adenosine (N-bz)-3’-CEP 2’-O-tBDSilyl-7-deaza-Guanosine (N-ibu)-3’-CEP 2’-O-tBDSilyl-7-deaza-Guanosine (N-Ac)-3’-CEP

2’-O-Methyl-7-deaza-Adenosine (N-bz)-3’-CEP 2’-O-Methyl-7-deaza-Guanosine (N-ibu)-3’-CEP 2’-O-Methyl-7-deaza-Guanosine (N-Ac)-3’-CEP

LNA-Adenosine (N-bz)-3’-CEP LNA-Cytidine (N-bz)-3’-CEP LNA-C-5-Methyl-Cytidine (N-bz)-3’-CEP LNA-C-5-Methyl-Cytidine (N-Ac)-3’-CEP LNA-Guanosine (N-ibu)-3’-CEP LNA-Guanosine (N-dmf)-3’-CEP LNA-Uridine-3’-CEP LNA-C-5-Methyl-Uridine -3’-CEP

2’-Deoxy-Adenosine (N-bz)-3’-CEP 2’-Deoxy-Cytidine (N-bz)-3’-CEP 2’-Deoxy-Cytidine (N-Ac)-3’-CEP 2’-Deoxy-Cytidine (N-ibu)-3’-CEP 2’-Deoxy-Guanosine (N-ibu)-3’-CEP 2’-Deoxy-Guanosine (N-dmf)-3’-CEP Thymidine-3’-CEP 2’-Deoxy-Uridine-3’-CEP 2’-Deoxy-Inosine-3’-CEP

2’-Deoxy-Adenosine (N-PAc)-3’-CEP 2’-Deoxy-Cytidin (N-PAc)3’-CEP 2’-Deoxy-Guanosine (N-tbPAc)-3’-CEP

GalNAc-L96-Succinate GalNAc C3 Phosphoramidite

Pseudouridine Phosphoramidite N1-Me-Pseudouridine Phosphoramidite

5-Methyl-deoxy Cytidine(N-Ac)-3’-CEP 5-Methyl-deoxy Cytidine(N-bz)-3’-CEP

Rainbow QuencherTM Phosphoramidites (4) Rainbow QuencherTM Solid Supports (2) Dark Quencher Phosphoramidites (5) Dark Quencher Solid Supports (3)

RBQ-C2 Phosphoramidite RBQ-C3 Phosphoramidite 5’-DMT-dT-C-5-RBQ-C2- 3’ Phosphoramidite 5’-DMT-dT-C-5-RBQ-C3-3’ Phosphoramidite

RBQ-C3 on CPG Support 5’-DMT-dT-C-5-RBQ-C3 CPG Support

Dark Quencher-534 Phosphoramidite Dark Quencher-579 Phophoramidite Dark Quencher-DMT-dT-C-5-534 Phosphoramidite Dark Quencher-DMT-dT-C-5-579 Phosphoramidite Dark Quencher-DMT-dU-C-5-579 Phosphoramidite

Dark Quencher-534 CPG Dark Quencher-579 CPG Dark Quencher-DMT-dU-C-5-579 Succinyl CPG

Chromophores & Phosphoramidites (20)

6-Carboxy-2’,4,4’,5’,7,7’-Hexachloro fluorescein 6-Carboxy-4,7,2’,7’-Tetrachloro fluorescein 5-Carboxy-fluorescein 6-Carboxy-fluorescein Cyanine-550 Cyanine-650 Cyanine 3.5 Phosphoramidite Cyanine 550 Phosphoramidite Cyanine 650 Phosphoramidite 6-Hexachloro-fluorescein (HEX) 6-Hex Phosphoramidite 6-TET 6-TET Phosphoramidite 6-FAM-dipivalate 6-FAM-dipivalate Phosphoramidite 6-TAMRA 6-TAMRA -Phosphoramidite 5-TAMRA 5-TAMRA -Phosphoramidite Biotin (tb)-CED phosphoramidite

2’-CEM Natural RNA Phosphoramidites (5)

2’-CEM-Adenosine (N-bz)-3’-CEP 2’-CEM-Adenosine (N-Ac)-3’-CEP 2’-CEM-Cytidine (N-Ac)-3’-CEP 2’-CEM-Guanosine (N-PAc)-3’-CEP 2’-CEM-Uridine-3’-CEP

5’-DMT Protected LNA-Nucleosides (7) 3'-DMT Protected Nucleosides (7) 3'- Amino Modified Nucleosides (17) 3’-DMT Protected LNA-Nucleosides (3) 2’-β-L-Deoxy Nucleosides (10) DMT- Protected 2’-Deoxy-α-Nucleosides (5) DMT-Protected 7-deaza Nucleosides (5) 5'-DMT-2’-O-tBDMS-7-deaza Protected Nucleosides (3) 5'-DMT-2’-O-Methyl-7-deaza Protected Nucleosides (3) DMT and Base Protected 2’-O-Acetyl-Ara Nucleosides (6) 5'-DMT-2'-O-TOM Protected Ribo Nucleosides (4) DMT and Base Protected 2’-Fluoro-deoxy-Nucleosides (8) Ara 2’-Fluoro-deoxy Nucleosides (8) DMT and Base Protected Ara 2’-O-Methyl Nucleosides (6) 5'-DMT Protected 2'-OMe nucleosides, Labile Protection (3) 5'-DMT-2'-O-Methyl Protected Nucleosides (8) 5'-DMT Protected Deoxy Nucleosides, Standard and Labile Protection (15) 5'-DMT Protected Ribo Nucleosides, Standard and Labile Protection (12) DMT Protected 2’-O-tBDMS Ribo Nucleosides with Labile Protection (11) 5'-DMT-2'-MOE-Protected Ribo Nucleosides (10) 5'-O-tBDMS Protected 2’-Fluoro-deoxy-Nucleosides (1)

5’-O-DMTr-LNA-Adenosine (N-bz) 5’-O-DMTr-LNA-Cytidine (N-bz) 5’-O-DMTr-LNA-C-5-Methyl-Cytidine (N-bz) 5’-O-DMTr-LNA-Guanosine(N-ibu) 5’-O-DMTr-LNA-Guanosine(N-dmf) 5’-O-DMTr-LNA-Thymidine 5’-O-DMTr-LNA-Uridine

3’-O-DMT-deoxy Adenosine(N-bz) 3’-O-DMT-deoxy Adenosine(N-PAc) 3’-O-DMT-deoxy Cytidine(N-Ac) 3’-O-DMT-deoxy Cytidine(N-bz) 3’-O-DMT-deoxy Guanosine(N-Ac) 3’-O-DMT-deoxy Guanosine(N-ibu) 3’-O-DMT-deoxy Thymidine

5'-O-DMT-3'-Amino-2'-OMe-Adenosine (N-bz) 5’-O-DMT-3’-Amino-2’-OMe-3’-deoxyAdenosine (N-Ac) 5'-O-DMT-3'-Amino-2'-OMe-Cytidine (N-Ac) 5'-O-DMT-3'-Amino-2'-OMe-Cytidine (N-bz) 5'-O-DMT-3'-Amino-2'-OMe-Guanosine (N-ibu) 5'-O-DMT-3'-Amino-2'-OMe-Uridine 5'-O-DMT-3'-Amino-2'-OMe-XyloUridine 5'-O-DMT-3'-Amino-2'-deoxy-Adenosine (N-bz) 5'-O-DMT-3'-Amino-2'-deoxy-Cytidine (N-bz) 5'-O-DMT-3'-Amino-2'-deoxy-Cytidine (N-Ac) 5'-O-DMT-3'-Amino-2'-deoxy-Guanosine (N-ibu) 5'-O-DMT-3'-Amino-2'-deoxy- Thymidine 5'-O-DMT-3'-Amino-2'-Fluoro-Adenosine (N-bz) 5'-O-DMT-3'-Amino-2'-Fluoro-Cytidine (N-bz) 5'-O-DMT-3'-Amino-2'-Fluoro-Cytidine (N-Ac) 5'-O-DMT-3'-Amino-2'-Fluoro-Guanosine (N-ibu) 5'-O-DMT-3'-Amino-2'-Fluoro- Uridine

3’-O-DMTr-LNA-Adenosine (N-bz) 3’-O-DMTr-LNA-Guanosine(N-dmf) 3’-O-DMTr-LNA-Thymidine

5’-O-DMTr-2’-β-L-deoxyadenosine(N-PAc) 5’-O-DMTr-2’-β-L-deoxyadenosine(N-bz) 5’-O-DMTr-2’-β-L-deoxycytidine(N-Ac) 5’-O-DMTr-2’-β-L-deoxycytidine(N-bz) 5’-O-DMTr-2’-β-L-deoxyguanosine(N-PAc) 5’-O-DMTr-2’-β-L-deoxyguanosine(N-ibu) 5’-O-DMTr-2’-β-L-deoxyguanosine(N-tBPAc) 5’-O-DMTr-2’-β-L-deoxyguanosine(N-iPrPAc) 5’-O-DMTr-β-L-Thymidine 5’-O-DMTr-2’-β-L-deoxyuridine

5’-O-DMTr-α-2’-deoxyadenosine (N-bz) 5’-O-DMTr-α-2’-deoxycytidine (N-bz) 5’-O-DMTr-α-2’-deoxycytidine(N-Ac) 5’-O-DMTr-α-2’-deoxyguanosine(N-ibu) 5’-O-DMTr-α-Thymidine

5’-DMT-7-deaza-Adenosine (N-bz) 5’-DMT-7-deaza-2’-deoxyadenosine(N-bz) 5’-DMT-7-deaza-guanosine(N-ibu) 5’-DMT-7-deaza-2’-deoxyguanosine(N-Ac) 5’-DMT-7-deaza-2’-deoxyguanosine(N-ibu)

5’-DMT-2’-O-tBDMS-7-deaza-Adenosine(N-bz) 5’-DMT-2’-O-tBDMS-7-deaza-Guanosine(N-ibu) 5’-DMT-2’-O-tBDMS-7-deaza-Guanosine(N-Ac)

5’-DMT-2’-OMe-7-deaza-Adnosine(N-bz) 5’-DMT-2’-OMe-7-deaza-Guanosine (N-ibu) 5’-DMT-2’-OMe-7-deaza-Guanosine (N-Ac)

5’-O-DMTr-2’-O-Acetyl-Ara-Aadenosine (N-bz) 5’-O-DMTr-2’-O-Acetyl-Ara-Cytidine (N-bz) 5’-O-DMTr-2’-O-Acetyl-Ara-Guanosine(N-ibu) 5’-O-DMTr-2’-O-Acetyl-Ara-Guanosine(N-dmf) 5’-O-DMTr-2’-O-Acetyl-Ara-Guanosine(N-Ac) 5’-O-DMTr-2’-O-Acetyl-Ara-Uridine

5’-O-DMTr-2’-O-TOM-Adenosine (N-Ac) 5’-O-DMTr-2’-O-TOM-Cytidine (N-Ac) 5’-O-DMTr-2’-O-TOM-Guanosine(N-Ac) 5’-O-DMTr-2’-O-TOM-Uridine

5’-O-DMTr-2’-Fluoro-deoxy Cytidine 5’-O-DMTr-2’-Fluoro-deoxy Adenosine (N-bz) 5’-O-DMTr-2’-Fluoro-deoxy Cytidine (N-bz) 5’-O-DMTr-2’-Fluoro-deoxy Cytidine (N-Ac) 5’-O-DMTr-2’-Fluoro-C-5-Methyl-deoxy Cytidine (N-bz) 5’-O-DMTr-2’-Fluoro-deoxy Guanosine(N-ibu) 5’-O-DMTr-2’-Fluoro Thymidine 5’-O-DMTr-2’-Fluoro-deoxy Uridine

5’-O-DMTr-2’-Fluoro-deoxy-Ara- Adenosine (N-bz) 5’-O-DMTr-2’-Fluoro-deoxy-Ara-Cytidine (N-bz) 5’-O-DMTr-2’-Fluoro-deoxy-Ara-Cytidine (N-Ac) 5’-O-DMTr-2’-Fluoro-deoxy-Ara- Guanosine(N-ibu) 5’-O-DMTr-2’-Fluoro-deoxy-Ara- Guanosine(N-dmf) 5’-O-DMTr-2’-Fluoro-Ara-Thymidine 5’-O-DMTr-2’-Fluoro-deoxy-Ara- Inosine 5’-O-DMTr-2’-Fluoro-deoxy-Ara- Uridine

5’-O-DMTr-2’-O-Methyl-Ara-Aadenosine (N-bz) 5’-O-DMTr-2’-O-Methyl-Ara-Cytidine (N-bz) 5’-O-DMTr-2’-O-Methyl-Ara-Cytidine (N-Ac) 5’-O-DMTr-2’-O-Methyl-Ara-Guanosine(N-ibu) 5’-O-DMTr-2’-O-Methyl-Ara-Guanosine(N-Ac) 5’-O-DMTr-2’-O-Methyl-Ara-Uridine

5’-O-DMTr-2’-OMethyl-Adenosine (N-PAc) 5’-O-DMTr-2’-OMethyl-Cytidine (N-PAc) 5’-O-DMTr-2’-OMethyl-Guanosine (N-PAc)

5’-O-DMTr-2’-OMethyl-Adenosine (N-bz) 5’-O-DMTr-2’-OMethyl-Cytidine (N-bz) 5’-O-DMTr-2’-OMethyl-Cytidine(N-Ac) 5’-O-DMTr-2’-OMethyl-C-5-Methyl-Cytidine (N-bz) 5’-O-DMTr-2’-OMethyl-Guanosine(N-ibu) 5’-O-DMTr-2’-OMethyl-Guanosine(N-Ac) 5’-O-DMTr-2’-OMethyl-Uridine 5’-O-DMTr-2’-OMethyl-C-5-Methyl-Uridine

5’-O-DMTr-2’-deoxyadenosine (N-bz) 5’-O-DMTr-2’-deoxyadenosine (N-PAc) 5’-O-DMTr-2’-deoxycytidine(N-Ac) 5’-O-DMTr-2’-deoxycytidine (N-PAc) 5’-O-DMTr-5-Me-2’-deoxycytidine(N-Ac) 5’-O-DMTr-2’-deoxycytidine (N-bz) 5’-O-DMTr-5-Me-2’-deoxycytidine(N-bz) 5’-O-DMTr-2’-deoxyguanosine(N-ibu) 5’-O-DMTr-2’-deoxyguanosine (N-PAc) 5’-O-DMTr-2’-deoxyguanosine (N-dmf) 5'-O-DMTr-2'-deoxyguanosine (N-tBPAc) 5’-O-DMTr-Thymidine 5’-O-DMTr-2’-deoxyInosine 5’-O-DMTr-2’-deoxyuridine 5’-O-DMT-5-Methyldeoxycytidine

5’-O-DMTr-Adenosine (N-bz) 5’-O-DMTr-Adenosine (N-PAc) 5’-O-DMTr-Cytidine (N-bz) 5’-O-DMTr-Cytidine(N-Ac) 5’-O-DMTr-Cytidine (N-PAc) 5’-O-DMTr-Guanosine (N-Ac) 5’-O-DMTr-Guanosine(N-ibu) 5’-O-DMTr-Guanosine (N-PAc) 5’-O-DMTr-Guanosine (N-tBPAc) 5’-O-DMTr-riboThymidine 5’-O-DMTr-Uridine 5’-O-DMTr-Inosine

5’-O-DMTr-2’-O-tBDMS-Adenosine (N-bz) 5’-O-DMTr-2’-O-tBDMS-Adenosine (N-Ac) 5’-O-DMTr-2’-O-tBDMS-Cytidine (N-bz) 5’-O-DMTr-2’-O-tBDMS-Cytidine(N-Ac) 5’-O-DMTr-2’-O-tBDMS-Guanosine(N-ibu) 5’-O-DMTr-2’-O-tBDMS-Guanosine (N-PAc) 5’-O-DMTr-2’-O-tBDMS-Guanosine(N-Ac) 5’-O-DMTr-2’-O-tBDMS-Guanosine (N-dmf) 5’-O-DMTr-2’-O-tBDMS-Guanosine (N-IPr-PAc) 5’-O-DMTr-2’-O-tBDMS-Inosine 5’-O-DMTr-2’-O-tBDMS-Uridine

5’-O-DMTr-2’-O-MOE-Adenosine (N-bz) 5’-O-DMTr-2’-O-MOE-Cytidine (N-bz) 5’-O-DMTr-2’-O-MOE-Cytidine(N-Ac) 5’-O-DMTr-2’-O-MOE-Guanosine(N-ibu) 5’-O-DMTr-2’-O-MOE-Guanosine (N-Ac) 5’-O-DMTr-2’-O-MOE-Guanosine (N-PAc) 5’-O-DMTr-2’-O-MOE-Guanosine (N-dmf) 5’-O-DMTr-2’-O-MOE-Uridine 5’-O-DMTr-2’-O-MOE-C-5-Methyl-Uridine 5’-O-DMTr-2’-O-MOE-Inosine

5'-O-tBDMS-2'-Fluoro-deoxy Adenosine(N-bz)

TMT Protected Nucleosides (4)

5’-TMT-deoxyAdenosine (N-bz) 5’-TMT-deoxyCytidine (N-bz) 5’-TMT-deoxyGuanosine (N-dmf) 5’-TMT-Thymidine

N-protected deoxy nucleoside (8) Natural Deoxy Nucleosides (19) Natural Ribo Nucleosides (9) Standard Nucleosides, Unprotected (6) Dideoxy Nucleosides (6) Alpha Nucleosides (4) 2’-β-L-DeoxyNucleosides (5) 2’-OMethyl Ribo Nucleosides (6) 2'-MOE Ribo Nucleosides (5) 7-deaza Nucleosides (8)

N-Benzoyl-2'-deoxy-adenosine N-Benzoyl-2'-deoxy-cytidine N-Acetyl -2'-deoxy-adenosine N-Pac -2'-deoxy-adenosine N-Acetyl-2'-deoxy-cytidine N-Acetyl-2'- Deoxyguanosine N-Isobutyryl-2'-Deoxyguanosin N-Pac -2'-Deoxyguanosine

2’-β-D-DeoxyadenosineMonohydrate 2’-β-D-Deoxycytidine(FreeBase) 2’-β-D-DeoxyguanosineMonohydrate β-D-Thymidine 2’-β-Deoxyuridine 2’-β-Deoxyinosine 5-Methyl-2’-deoxycytidine 5-Iodo-2’-deoxyuridine 5-Bromo-2’-deoxyuridine 5-Iodo-2’-deoxycytidine 8-Bromo-2’-deoxyadenosine 8-Bromo-2’-deoxyguanosine 6-Thio-2’-deoxyguanosine 4-Thio-2’-deoxyuridine 4-Thio-Thymidine 2’-Fluoro-Deoxy-Adenosine 2’-Fluoro-Deoxy-Cytidine 2’-Fluoro-Deoxy-Guanosine 2’-Fluoro-Deoxy-Uridine

5-Iodo-Cytidine 8-Bromo-Adenosine 8-Bromo-Guanosine 4-Thio-Uridine 5-Methyl-Cytidine 5-Bromo-Cytidine 2,2'-Anhydro-rU 5-Iodo-Uridine 5-Bromo-Uridine

Adenosine Cytidine Guanosine Uridine 5-Methyl Uridine Inosine

2’,3’-β-Dideoxyadenosine 2’,3’-β-Dideoxycytidine 2’,3’-β-Dideoxyguanosine 2’,3’-β-Dideoxythymidine 2’,3’-β-Dideoxyuridine 2’,3’-β-Dideoxyinosine

2’-α-D-Deoxyadenosine 2’-α-D-Deoxycytidine 2’-α-D-DeoxyguanosineMonohydrate α-D-Thymidine

2’-β-L-Deoxyadenosine 2’-β-L-Deoxycytidine 2’-β-L-Deoxyguanosine 2’-β-L-DeoxyUridine β-L-Thymidine

2’-O-Methyl Adenosine 2’-O-Methyl Cytidine 2’-O-Methyl Guanosine 2’-O-Methyl Uridine 2’-O-Methyl Inosine 2’-O-Methyl ribothymidine

2'-MOE-Adenosine 2'-MOE-Cytidine 2'-MOE-Guanosine 2'-MOE-Uridine 2'-MOE-Inosine

7-deaza-2’-deoxyadenosine 7-deaza-2’,3’-dideoxyadenosine 7-deaza-Adenosine 7-deaza-7-Iodo-2’-deoxyadenosine 7-deaza-7-Iodo-2’-deoxyguanosine 7-deaza-2’-deoxyguanosine 7-deaza-Inosine 7-deaza-2’-deoxyinosine

5’,3’-Bis-Silyl Ribo Nucleosides (5)

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl) Adenosine (N-Ac) 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl) Cytidine (N-Ac) 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl) Guanosine (N-ibu) 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl) Guanosine (N-PAc) 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl) Uridine

HIGH PURITY REAGENTS (12) HIGH PURITY DRY SOLVENTS (13) Trityl Chlorides (4) Activation Reagents (4) Phosphoramidite Reagents (8)

4-Isopropylphenoxy Acetic Acid 4-Isopropylphenoxy Acetyl Chloride 4-tert-butylphenoxy Acetic Acid 4-tert-butylphenoxy Acetyl Chloride Phenoxy Acetyl Chloride p-Toluoyl Chloride O-Phenyl Chlorothionoformate 5-Methyl-2-Nitrobenzyl Chloride Potassium Chloride Potassium Bromide 3-Hydroxypropionitrile 6-Amino-1-Hexnol

Dichloromethane (Anhydrous) Toluene (Anhydrous) Pyridine (Anhydrous) N,N-Dimethylformamide (Anhydrous) Tetrahydrofuran (Anhydrous) Dimethylsulfoxide (Anhydrous) N,N-Diisopropylethylamine (Anhydrous) Acetone (Anhydrous) 2,6-Lutidine (Anhydrous) Ethyl Acetate (Anhydrous) Chloroform (Anhydrous) Hexanes (Anhydrous) Isopropyl Alcohol

4-Methoxytriryl Chloride 4,4’-Dimethoxytriryl Chloride 4,4’,4”-Trimethoxytriryl Chloride 4,4’-Dimethoxytriryl Alcohol

5-Ethylthio-1H-Tetrazole (ETT) 5-Benzylthio-1H-Tetrazole (BTT) 4,5-Dicyanoimidazole (DCI) Diisopropylammonium tetrazolide

2-Cyanoethyl N,N-diisopropylchloro phosphoramidite (Chloro reagent) 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite Dichloromethoxy phosphite Methyl N,N-diisopropylchloro phosphoramidite Ethyl N,N-diisopropylchlorophosphoramidite Bis(diisopropylamino) Chlorophosphine 2-Cyanoethyl dichlorophosphite Diethyl N,N-diisopropylphosphoramidite

Acetonitrile Anhydrous (3) Deblock Solution (13) Activation Solution (5) Capping Solution A (9) Capping Solution B (10) Oxidation Solution (7) DEA Solution (2) DDTT Solution (2) Activation Solution (ETT & BTT) (6)

Acetonitrile Anhydrous Anhydrous Acetonitrile (Phosphoramidite Diluent Grade) Acetonitrile (HPLC Grade)

Deblock Solution (3% Trichloroacetic Acid/ Dichloromethane) Deblock Solution (3% Dichloroacetic Acid / Toluene) Deblock Solution (5% Trichloroacetic Acid / Dichloromethane) Deblock Solution (3% Dichloroacetic Acid / Dichloromethane) Deblock Solution(2.5% Dichloroacetic Acid / Dichloromethane) Deblock Solution (15% Trichloroacetic Acid/ Dichloromethane) Deblock Solution(5% Dichloroacetic Acid / Toluene) Deblock Solution (15% Dichloroacetic Acid/ Toluene) Deblock Solution (1.1% Trifluoroacetic Acid / Toluene) Deblock Solution (3% Trichloroacetic Acid/ Toluene) Deblock Solution (7% Dichloroacetic Acid/ Toluene) Deblock Solution (10% Dichloroacetic Acid/ Toluene) Deblock Solution (2% Trichloroacetic Acid/ Dichloromethane)

DCI Activation Solution (0.25M 4,5-dicyanoimidazole solution in Acetonitrile) DCI Activation Solution (0.30M) DCI Activation Solution (0.45M) DCI Activation Solution (0.60M) DCI Activation Solution (0.50M)

Capping Solution A{Acetic Anhydride/Pyridine/Acetonitrile (10:10:80)} Capping Solution A{Acetic Anhydride/Pyridine/THF(10:10:80)} Capping Solution A {Acetic Anhydride/Lutidine/THF (10:10:80)} Capping Solution A {20% N-Methylimidazole / Acetonitrile} Capping Solution A {16% N-Methylimidazole / Acetonitrile} Capping Solution A {25% Acetic Anhydride / Acetonitrile} Capping Solution A {(10% Phenoxy acetic Anhydride /Pyridine (10%)/ Acetonitrile Solution-A1 + Solution-A2 (80%)} Capping Solution A {10% Phenoxyacetic anhydride in THF/Pyridine} Capping Solution A (For Pac Chemistry) {5% Phenoxyacetic anhydride in THF/Pyridine}

Capping Solution B {16% N-Methylimidazole / Tetrahydrofuran} Capping Solution B {10% N-Methylimidazole / Tetrahydrofuran} Capping Solution B {20% N-Methylimidazole / Tetrahydrofuran} Capping Solution B 1 {40% Acetic Anhydride / Acetonitrile} Capping Solution B 2 { 40% Pyridine/Acetonitrile} Capping Solution B 2 {60% Symmetrical collidine with Acetonitrile} Capping Solution B 2 {60% Lutidine / Acetonitrile} Capping Solution B {10% N-Methylimidazole / Pyridine / Tetrahydrofuran (10:10:80)} Capping Solution B {Acetonitrile / 2,6-Lutidine/N- methylimidazole(50:30:20)} Capping Solution B {(Acetonitrile/Pyridine/N-Methylimidazole)(50:30:20)}

Oxidation Solution (0.02M) {THF (76:0%): Iodine (0.02M): Pyridine (8%): Water (16%)} Oxidation Solution (0.01M) {Tetrahydrofuran/Iodine 0.01M/Pyridine/Water} Oxidation Solution 0.1M{THF (76:0%): Iodine (0.1M): Pyridine (8%): Water (16%)} Oxidation Solution (0.05M){Iodine (0.05M): Pyridine (90%): Water (10%)} Oxidation Solution (0.58 w/w%){(Acetonitrile (56.84w/w%) / Iodine (0.58w/w%)/ Pyridine (6.76w/w%) / Water(35.43w/w%) / Potassium Io} Oxidation Solutions {THF (70:0%): Iodine (0.02M): Pyridine (20%): Water (10%)} Oxidation Solutions (0.02M){THF (78:0%): Iodine (0.02M): Pyridine (20%): Water (2%)}

DEA Solution{20 % Diethylamine/Acetonitrile} DEA Solution{5 % Diethylamine/Acetonitrile}

DDTT Solution (0.1M){DDTT Solution (0.05M in Pyridine)} DDTT Solution (0.1M){DDTT Solution (0.1M in Pyridine)}

ETT Activation Solution ( 0.60M 5-Ethylthio-1H-Tetrazole/Acetonitrile) ETT-Activation Solution (0.25M 5-Ethylthio-1H Tetrazole in Anhydrous Acetonitrile) BTT Activation Solution (0.30M  5-Benzylthio-1H-Tetrazole  in  Acetonitrile) ETT Activation Solution (0.50M) BTT Activation Solution (0.20M) ETT Activation Solution (0.45M)

Lab Supporters (2) Ancillary Reagents Packaging Solutions (9)

Drying Traps Returnable / Reuseable Safety Container

Amber Glass Standard bottle (24-400) Amber Glass Standard bottle (28-400) Amber Glass Standard bottle (28-410) Amber Glass Standard bottle (28-410) Amber Glass Standard bottle with Handle (38-439) Amber Glass Standard bottle with Handle (38-439) Amber Glass GL 45 Standard bottle (GL 45) Amber Glass GL45 Standard bottle (GL 45) Amber Glass GL45 Standard bottle (GL 45)